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tecovirimat will enhance the level or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Check. Tecovirimat can be a weak inhibitor of CYP2C8 and CYP2C19. Monitor for adverse results if coadministered with delicate substrates of those enzymes.butabarbital will minimize the level or outcome of diazepam by affecting hepati